P036 Pyoderma gangrenosum induced by Amgevita in a seropositive rheumatoid arthritis patient: a paradoxical effect of adalimumab?

A Case of Pyoderma Gangrenosum in a Patient with Rheumatoid Arthritis Treated with Abatacept.

Adalimumab treatment for pyoderma gangrenosum.

A 47-year-old woman was referred to Washington University dermatology clinic for a nonhealing ulcer on her right shin of 8 months’ duration. She reported having had a similar ulcer on her left shin 6 years ago. The patient’s medical history was significant for non–insulin-dependent diabetes mellitus, hypertension, and osteoarthritis. On examination, she was found to have a 2 3-cm punched-out ul...

A case of surgically treated peristomal pyoderma gangrenosum in a patient with rheumatoid arthritis

Peristomal pyoderma gangrenosum (PPG) is a rare subtype of pyoderma gangrenosum that is difficult to diagnose and treat. It is characterized by the rapid progression of painful necrotic ulcer surrounding an area of abdominal stoma. It is almost exclusively associated with inflammatory bowel disease even after bowel surgery and is associated with significant morbidity. Diagnosis of pyoderma gang...

[Pyoderma gangrenosum associated with rheumatoid arthritis: a case report].

Pyoderma gangrenosum is a chronic inflammatory dermatosis, which is associated with non-infectious systemic diseases such as rheumatoid arthritis and inflammatory bowel disease. It is more common in adults and may present with four distinct clinical forms, all leading to ulceration of the skin affected. Its diagnosis is clinical and demands exclusion of other causes. Treatment should be perform...

Use of infliximab in a patient with pyoderma gangrenosum and rheumatoid arthritis.

Pyoderma gangrenosum (PG) is characterized by ulcerative skin lesions. Infliximab (IFX) may promote PG healing in patients with inflammatory bowel disease, but whether IFX is effective for treating PG in patients with rheumatoid arthritis (RA) has not reported. We report the case of a 53-year-old woman with PG complicated by RA who was treated using IFX therapy. This case suggests that IFX ther...